For the constant secretion model, we inferred a secretion rate of 1190 U/mL(hour), while for the pulsed secretion rate, we inferred a baseline secretion rate of 100 U/mL(hour), which can rise to 2760 U/mL(hour) when extracellular IFN levels reach 1120 U/mL, which occurred between 18 h and 24 h of infection (Rand et al. estimated a secretion rate of 1300 U/mL(hour), roughly comparable to our values). Here, IFNA1 is linked to infection.