Genetic analysis consisted of detecting albumin in the adrenal gland biopsy via RNAin situ hybridization, which confirmed the hepatoid characterization of the sample.This test is considered highly sensitive in poorly differentiated HCC versusimmunohistochemistry, and the combination of Arg-1 and genetic analysissignificantly improves diagnostic accuracy.13 The gene discussed is ALB; the disease is hepatocellular carcinoma.