Triple-negative breast cancer does not express receptors for estrogen,progesterone, or human epidermal growth factor receptor 2/neu, and can be suggestiveof heritable breast cancer, especially in women diagnosed at age < 60years.14 Internationalguidelines recommend that individuals with triple-negative breast cancer be referredfor genetic testing or counseling. The gene discussed is ERBB2; the disease is triple-negative breast carcinoma.