BRIP1 and breast cancer: Among the hubs of the 6 modules, 5 of them (PTPN22, BRIP1, CEACAM6, LTF, and CCNT1) have been previously found to be associated with breast cancer [46][47][48][49][50][51][52][53], and the other one, MXRA5, has been reported to be related to non-small cell lung cancer[54][55].