To determine whether BCL family can also facilitate gene editing in other cell lines, we tested the effects of BCL-XL, BCL2, and MCL1 in mouse ESCs, HEK293T (human embryonic kidney cells), K562 (human erythroleukemia cells), and Jurkat (T-cell leukemia) cells. The gene discussed is BCL2L1; the disease is T-cell leukemia.