IL2 and infection: We have also demonstrated that H. polygyrus infection results in the preferential trafficking of LTi-like ILC3s to the MLN (Mackley et al., 2015), pointing again to a diminished role of ILC2s in immunity to this infection, while a recent study reported only modest reduction in adult H. polygyrus worm burdens in mice in whom ILC2 numbers were expanded fivefold with IL-2:anti-IL-2 complex (Pelly et al., 2017).