PROS1 and hyperinsulinemic hypoglycemia, familial, 4: As reported in Table 1, we identified an association of migraine with aPLs positivity (OR=2.6, 95% CI 1.5-4.7, p=0.001) and with free protein S deficiency (OR=4.7, 95% CI 1.6-14.0, p=0.002).