Univariate analyses revealed associations between OS and age (>60/≤60, year); GAR (>0.80/≤0.80); gender (male/female); GPS (2/0, 1); lymphatic invasion (presence/absence); lymph node metastasis (presence/absence); maximum tumor size (>4.0/≤4.0, cm); NLR (>2.7/≤2.7); operative bleeding (>320/≤320, mL); PNI (<45/≥45); serosal invasion (presence/absence); the serum levels of albumin (<3.5/≥3.5, g/dL), CA19‐9 (>10/≤10, U/mL), CEA (>5/≤5, ng/mL), and CRP (>1.0/≤1.0, mg/dL); TNM stage (II, III/I); and venous invasion (presence/absence) (Table 3). Here, CEACAM5 is linked to metastatic malignant neoplasm in the lymph nodes.