Immunosuppression in sepsis thus provides a novel understanding of the disorder as well as a new therapeutic approach.9 Therefore, investigators have attempted to stimulate innate and adaptive immune systems with IFN‐γ, granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), or granulocyte colony‐stimulating factor G‐CSF (Figure 3). This evidence concerns the gene CSF2 and Sepsis.