NFKB1 and Sepsis: Whereas hyper‐inflammatory responses of sepsis require NF‐κB for the production of proinflammatory cytokines and the activation by caspase cleavage, both NF‐κB and caspases concurrently induce the apoptosis of immune cells.3 Consistent with this, a concurrent apoptotic response has been shown to be present in sepsis in association with the proinflammatory response.13