Michalk et al [26] reported a 6.3% incidence of MDM2 amplification in esophageal carcinomas (adenocarcinoma and squamous cell carcinoma), and Schoolmeester et al [44] found an incidence of 5% (2 of 43 cases) in endometrial stromal tumors. The gene discussed is MDM2; the disease is squamous cell carcinoma.