Using piggyBac transposon-mediated mutagenesis combined with next-generation sequencing, one recent report also found that some new candidate genes such as deoxycytidine kinase and BMP-2-inducible protein kinase could be associated with flu-resistance in HG3 cells, a human modified CLL cell line [29]. The gene discussed is DCK; the disease is B-cell chronic lymphocytic leukemia.