This is because several studies have proven, especially in liver cancer, that the effect of GABA is associated with cell migration.22,28 Indeed, breast cancer cell lines, MDA-MB-231 and MCF-7, show differential susceptibilities in apoptosis induced by RBBP6 silencing alone or in combination with either camptothecin or GABA. This evidence concerns the gene RBBP6 and liver cancer.