However, at the post-weaning period, LA did not have significant impact on these pathways in RuD, but significantly changed caffeine metabolism pathway in the CoM and five pathways (cell cylce, EGFR tyrosine kinase inhibitor resistance, oxytocin signaling, mRNA surveillance and Fanconi anemia pathway) in IlM. The gene discussed is OXT; the disease is Fanconi anemia.