Moreover, we analyzed the mRNA expression data from TCGA using GEPIA database and found that the expression level of RIF1 positively correlated with that of MYC (r = 0.28, P < 0.001, Fig. 8c) and CCND1 (r = 0.14, P = 0.0016, Fig. 8d) in NSCLC tissues. The gene discussed is RIF1; the disease is non-small cell lung carcinoma.