AKT1 and neoplasm: We measured the proliferation of the IGROV1Res and OAW42Res tumor cell lines treated with increasing concentrations of GDC0032, in the absence or presence of inhibitors such as AEW541 (IGF1R inhibitor), PHA-665752 (MET inhibitor), MK2206 (AKT inhibitor), and others (Supplementary Fig. 2B).