Additionally, in two models of cholestatic liver disease induced by BDL after 3 and 7 days of surgery14 and the Mdr2-/- mouse, a model of inflammation-induced cholestatic liver injury, fibrosis, and cancer15, we found an inverse correlation between GNMT levels and miR-873-5p expression (Fig. 1c, d). The gene discussed is GNMT; the disease is Cholestatic liver disease.