FOLH1 and neoplasm: Interestingly, although the observed effects of the respective fluorescent dye on the PSMA-targeting, clearance kinetics, and biodistribution pattern of 111In-DOTA-Lys(Nε-IRDye800CW)-Sub-KuE, IRDye800CW-68Ga-HBED-CC-KuE, and 68Ga-PSMA-I&F are fundamentally different, the tumor-to-background ratios for the 3 compounds were similar (tumor-to-blood, tumor-to-liver, tumor-to-intestines, and tumor-to-muscle: 1.4, 5.8, 7.7, and 11.6 [111In-DOTA-Lys(Nε-IRDye800CW)-Sub-KuE (31)]; 4.5, 4.9, 5.7, and 4.8 [IRDye800CW-68Ga-HBED-CC-KuE (32)]; and 2.1, 5.2, 9.6, and 9.6 [68Ga-PSMA-I&F], respectively).