Since the cells from the healthy controls that were used in Fig. 4 and Additional file 1 (Figure S3) may react differently to treatment than the cells from RA patients, the experiment was repeated using sorted CCR6+ memTh cells from treatment-naive early RA patients cultured with RASF serving as a proof of principle (Fig. 5 and Additional file 1: Figure S4). Here, CCR6 is linked to rheumatoid arthritis.