In this manuscript, we have used the online tools cBioportal, DAVID6.8 and SurvExpress in order to (i) evaluate MUC4 expression in various carcinomas, (ii) identify genes that are correlated with MUC4 and evaluate their roles and (iii) propose MUC4/MUC16/MUC20 combination as a prognostic marker of pancreatic, colon and stomach cancers. The gene discussed is MUC20; the disease is carcinoma.