Besides expected inter-patient expression differences due to different origin of pDCIS and DCIS with IBC component, MMP11 and COL10A1, significantly progressed from ‘low expression’ in pDCIS, to ‘intermediate expression’ in DCIS and further to ‘high expression’ in the corresponding IBC, with the differences between pDCIS and DCIS of DCIS/IBC mixed tumours. Here, COL10A1 is linked to ductal breast carcinoma in situ.