Also, at the mRNA level, expression of IL-8 (23.91 ± 7.88-fold, p < 0.0001), MCP-1 (1.94 ± 0.21-fold, p = 0.0008) and OPN (3.38 ± 0.70-fold, p = 0.0012) were significantly increased in CBD treated cells (n = 8). This evidence concerns the gene SPP1 and red-green color blindness.