Sensitization rates in 5 study-samples selected from hospital-admitted subjects varied according to different criteria to define AS allergy, from 0.5% with a combination of both positive SPTs and >0.7 kU/L IgE (Falcão H 2008) [54] to 20% when IgE >0.35 kU/L were sufficient to be considered positive (Daschner A 1998) [59]. This evidence concerns the gene IGHE and Allergy.