DDIT4 and ulcerative colitis: Notably, in contrast to active Crohn’s disease, REDD1 or Beclin-1 expression in colonic neutrophils, and NETosis are diminished according to the distance from the inflamed intestinal area, suggesting that neutrophil autophagy could be a candidate diagnostic and disease severity target in ulcerative colitis (Angelidou et al., 2018).