IL1B and familial Mediterranean fever: Consisting with this, whole transcriptome analysis in neutrophils derived from FMF patients uncovered the role of autophagy-related protein regulated in development and DNA damage responses 1 (REDD1) as a key regulator linking environmental stress with autophagy-mediated NETosis and NET-associated IL-1β autoinflammation (Skendros et al., 2017).