In a NSCLC cohort of 836 patients (2,276 lesions), Miller et al. showed that lung adenocarcinoma histology (1-year incidence of 5.9% vs. 3.1–3.9% for other histologies), and ALK (HR 6.36, p < 0.001), but not EGFR lesions had increased rates of RN. This evidence concerns the gene ALK and non-small cell lung carcinoma.