Interestingly, GASCs expressing high levels of CXCL14 have been shown to upregulate lncRNA UCA1 and downregulate miR-182, with miR-182 directly binding to PFKFB2 to modulate CXCL14 secretion, glycolysis, and the invasion of glioma cells (101). This evidence concerns the gene UCA1 and central nervous system cancer.