Recently, the CRSIPR/Cpf1-mediated dystrophin knock-out pigs, and phospholamban knock-in pigs with a 3-nt deletion in the presence of a single-stranded oligo donor, have been established as a Duchenne muscular dystrophy (DMD) and dilated cardiomyopathy (DCM) models, respectively. This evidence concerns the gene PLN and Duchenne muscular dystrophy.