Authors renowned for having published authoritative monographs on GH (104) and insulin (105) have paved the way for novel and more relevant approaches, as shown by the well-documented detrimental effects generated by the exogenous administration of GH (106) contrasting with the beneficial impact of added insulin which allows normalization of harmful hyperglycemia and attenuation of the levels of cytokines, APRs and most pro-inflammatory biomarkers (107). Here, INS is linked to Hyperglycemia.