NLRP3 and cerebrovascular disorder: The NLRP3 inflammasome has been reported to play a vital role in cerebrovascular diseases, and many signaling pathways mediated by the NLRP3 inflammasome are highly involved in the onset and progression of both ischemic and hemorrhagic stroke (Zhou et al., 2016; Barrington et al., 2017; Freeman et al., 2017; Ye et al., 2017; Fann et al., 2018; Nasoohi et al., 2018).