Interestingly, this study showed that GLYX-13 prevents hippocampal N-methyl-D-aspartate receptor subtype 2B—Disrupted in schizophrenia 1 (GluN2B-DISC1) signaling and behavioral changes induced by schizophrenia-mimetic drug MK801 in mice. This evidence concerns the gene GRIN2B and schizophrenia.