Pro-inflammatory cytokines IL-2, IL-12 and IFN-γ are associated with good prognosis in cancer, whilst an increase of immunosuppressive cytokines IL-6, IL-10 and TGF-β correlates to poor outcome (Lippitz 2013; Fridman et al. 2012; Mantovani et al. 2008; Guo et al. 2012; Vesely et al. 2011). This evidence concerns the gene TGFB1 and cancer.