Apart from one frameshift insertion in BCAR1, there were no rare loss-of-function variants of FLT4, KDR, VEGFA, FGD5, IQGAP1, FOXO1, or PRDM1 identified in the genome sequencing data of 7231 individuals with autism from the MSSNG database (https://www.mss.ng/#). The gene discussed is IQGAP1; the disease is autism.