PLA2G6 and neurodegeneration with brain iron accumulation 2A: The PLA2G6 (PARK14) gene encodes a group VIA calcium-independent phospholipase A2 beta enzyme, which has been proved as a pathogenic factor for neurodegenerative disorders with increased basal ganglia iron accumulation, such as infantile neuroaxonal dystrophy (INAD) and neurodegeneration with brain iron accumulation (NBIA)11.