GH1 and acromegaly: Finally, at variance with its nearly universal inhibitory actions, low (pM) concentrations of SRIF stimulate in vitro GH release on cultured pituitary cells derived from pigs (Luque et al., 2006) and nonhuman primates (Cordoba-Chacon et al., 2012b) and from human somatotroph adenomas (Matrone et al., 2004).