Furthermore, similar results were obtained using SST2-preferring or selective analogs in endogenously SST2-expressing cells [e.g., pituitary tumors (Ferrante et al., 2006; Hubina et al., 2006; Theodoropoulou et al., 2006; Horiguchi et al., 2009; Peverelli et al., 2017), insulinoma (Aoki et al., 2014), glioma (Barbieri et al., 2009), normal and tumoral pancreatic acinar cells (Charland et al., 2001), or thyroid cells (Medina et al., 1999)]. Here, CORT is linked to central nervous system cancer.