SSTR1 and pancreatic adenocarcinoma: SST1 was also found uniquely expressed in stellate cells of pancreatic adenocarcinoma, and its activation by pasireotide reduced chemoprotective and prometastatic features of these fibroblastic cells by reducing IL-6 and collagen-1 secretion (Duluc et al., 2015; Moatassim-Billah et al., 2016).