In contrast, among those carrying at least one copy of the minor allele for LEPR SNPs, the magnitude of the acetaminophen use effect on asthma was highly pronounced among males (rs17415296: aPR = 6.83,), but not among females (rs17415296: aPR = 1.22; Fig. 1, see Additional file 1: Table S3). The gene discussed is LEPR; the disease is asthma.