When UTMZ cells were injected into the flank of nude mice, the mean tumor weight was significantly lower (0.18 ± 0.09 g vs 0.92 ± 0.1 g) in the group that received IGFBP6-transfected UTMZ cells than in the control group that received empty vector-transfected UTMZ cells (Fig. 6d). The gene discussed is IGFBP6; the disease is neoplasm.