CEACAM5 and colorectal neoplasm: Studies on the anticancer alkaloid vindesine (VDS) conjugates of the anti-carcinoembryonic antigen (CEA) antibodies against a colorectal tumor xenograft reveal that VDS−11.285.14 (IgG1) conjugate can produce an almost complete and lasting suppression of tumor growth, and it is considerably less toxic than free VDS in Balb/c mice [33].