However, 3 observations from these studies are of particular interest: (a) the role of anti‐Ascaris IgE as an important risk factor for a mild wheezing illness in rural populations where STH are endemic; (b) the role of STH infections in attenuating the associations between atopy and wheeze; and (c) the potential role of maternal and childhood STH infections in modulating risk of wheezing illness by school age. Here, IGHE is linked to infection.