PLG and hyperinsulinemic hypoglycemia, familial, 4: Given that both the degree of elbow stiffness (Brinsden et al. 2008; King and Faber 2000; Mansat et al. 2000) and plasmin activity reduction (Amaro et al. 2017; Gibson et al. 2017) have been related to the severity of injury, we examined if a focal peri-elbow soft tissue injury, in conjunction with an investigator-imposed plasminogen deficiency, was sufficient to model trauma-induced elbow stiffness.