Insulin resistance and oxidative stress stimulate IKKβ- (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) dependent NF-κB (nuclear factor kappa-light-chain-enhancer of activated B-cells) signaling pathway and promote hepatocyte survival in addition to their crucial role in liver inflammatory responses [60]. This evidence concerns the gene IKBKB and Insulin resistance.