In Mo2 as well as Mo3 monocytes, CX3CR1 expression was strongly decreased in HD patients compared to the healthy cohort and the dialysis procedure even further reduced CX3CR1 expression (Mo2: CON/HD pre: p = 0.009, CON/HD post: p < 0.0001, HD pre/post: p = 0.003; Mo3: CON/HD pre: p = 0.02, CON/HD post: p = 0.0006, HD pre/post: p = 0.0009). The gene discussed is CX3CR1; the disease is Huntington disease.