Microarray analysis independently confirmed anti-apoptotic effects of Sandalore® (Fig. 6, Supplementary Fig. 5, and Supplementary Data 1), since transcripts of pro-apoptotic genes were significantly downregulated (e.g., TP53AIP1: -10.27×), while anti-apoptotic genes were significantly upregulated (e.g., FGF-2: +7.83×) in HFs treated short term with Sandalore® (6 h, Supplementary Fig. 5a, b and Supplementary Data 1). This evidence concerns the gene FGF2 and Hand-foot syndrome.