P2RY12 and astrocytoma (excluding glioblastoma): For this reason, in the experiments described below, we compared CLCbSallA with CLCbWT in HeLa cells when we tested effects on endocytosis that were likely to affect a range of cargoes, and CLCbS204A with CLCbWT when we were specifically measuring P2Y12 uptake in 1321N1 astrocytoma cells.