ACE2 and metabolic syndrome: Remarkably, although there were no significant differences on LDL-C and CHOL levels between non-diabetic and diabetic individuals, but we found that T2D patients with the high diabetic risk or control genotypes of 4 diabetic risk related ACE2 SNPs (rs1978124, rs2048683, rs4646156 and rs879922) had a higher risk to develop high levels of LDL-C (≥ 1.8 mmol/L) and CHOL (≥ 5.2 mmol/L) adjusted for gender, age, BMI, T2D and ACE2 SNPs, which further suggests that the 4 ACE2 SNPs may be potential influential factors of dyslipidemia in diabetics.