As shown in Fig. 1, T2D related ACE2 SNP rs4646188 and rs879922 were associated with increased SBP (P = 0.006 and < 0.001) and DBP (P = 0.004 and < 0.001) while rs1978124 was not (both P > 0.05). The gene discussed is ACE2; the disease is type 2 diabetes mellitus.