This pathway may implicate inflammatory biomarkers with shorter half-life, such as interleukin-6, TGF-β, and TNF-α, because studies have shown that Tocovid reduced serum creatinine and ameliorated diabetic nephropathy through downregulation of TGF-β and TNF-α in diabetic rats [12]. The gene discussed is TGFB1; the disease is diabetic kidney disease.