FLT1 and colorectal carcinoma: MiR-200c has also been shown to function as an oncogene in CRC played an important role in regulation of EMT and metastatic behavior in CRC results in the negative regulation of its gene targets zinc finger E-box binding homeobox 1 (ZEB1), ETS proto-oncogene 1, transcription factor (ETS1) and fms related tyrosine kinase 1 (FLT1), which, in turn, regulates the EMT markers (E-cadherin and vimentin) [59].