Of the patients eligible for intensification (HbA1c ≥7.0% [≥53.0 mmol/mol]), the subgroup who intensified with basal–bolus insulin had a higher proportion of men, were younger, had a lower duration of diabetes, and had higher body weight and BMI at the index date compared with the subgroup who intensified with premix insulin (S1 Table). Here, INS is linked to diabetes mellitus.