Finally, we tested all gene co-expression modules for evidence of enrichment of genes associated with PD (as determined using VEGAS) and results showed a significant enrichment within MyD88-containing modules in the putamen and medulla (putamen, enrichment p value = 2.20 × 10−3; medulla, enrichment p value = 2.92 × 10−2; Supplementary Table 1). The gene discussed is MYD88; the disease is Parkinson disease.