TGFB1 and neoplasm: To further determine the mechanism responsible for the effect of CSCs-exosomes on tumor progression, we detected the expression of some genes known to be important to tumor growth (Bax, p53, Bcl2), metastasis, and angiogenesis (TGFβ1, NFκB, MMP9, TIMP1, and VEGF) by qPCR.