IL6 and colitis: Treatment with EL also caused colitis; it increased colon shortening [F(1,14) = 52.600, p < 0.001] and myeloperoxidase activity [F(1,14) = 120.126, p = 0.001] and increased TNF-α [F(1,14) = 284.786, p < 0.001], IL-1β [F(1,14) = 818.012, p < 0.001], and IL-6 [F(1,14) = 72.483, p < 0.001] expression in the blood (Fig. 5n–u).