These are reminiscent of phenotypic traits of Fragile X Mental Retardation 1 (Fmr1) knockout (KO) mice, a model for Fragile X Syndrome (FXS), which is associated with a loss of an mRNA binding protein, Fragile X Mental Retardation Protein (FMRP) [11–13]. The gene discussed is FMR1; the disease is fragile X syndrome.